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Posted by john on August 26th, 2007 — in Allegra Top News
SUNDAY, Aug. 26 (HealthDay News) — Ragweed season, which lasts from about mid-August to October in many parts of the United States, can bring misery to the estimated 36 million Americans with seasonal allergic rhinitis (hay fever).
Symptoms such as sneezing, runny noses, swollen, itchy watery eyes are so severe that they disrupt a person’s ability to function normally at work or school, says the American Academy of Allergy, Asthma & Immunology (AAAAI).
The academy notes that almost 80 percent of people with seasonal allergies suffer sleep problems, resulting in daytime fatigue and poor concentration. Each year, ragweed-related allergies cause more than 3.8 million lost days of work and school.
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The AAAAI offers some tips on how to reduce exposure to ragweed:
* Avoid areas where ragweed plants thrive, such as ditches, roadsides, riverbanks, vacant lots, and the edges of wooded areas.
* Keep windows closed during ragweed season in order to prevent pollen from getting into your home. Use air conditioning, which cools, cleans and dries the air.
* Keep your car windows closed.
* Limit the amount of time you spend outdoors when pollen counts are high.
* After you spend time outside, take a shower to wash pollen from your skin and hair.
* Minimize your exposure to other allergens during ragweed season. Hay fever symptoms are often the result of cumulative exposure to multiple allergens.
* Start taking allergy medications 10 to 14 days before peak ragweed season in your area.
* Get up-to-date pollen information from the National Allergy Bureau
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Posted by john on August 19th, 2007 — in Allegra Top News
Musicians For Harmony Founder Allegra Klein has returned from Erbil, Iraq, following her participation in a landmark event–The National Unity Performing Arts Academy. The free Academy–the first project of its kind in the history of Iraq–created an oasis of artistic expression for over 300 of the country’s aspiring performers. It was, says Klein, “perhaps the most rewarding and gratifying experience of my life.”
Klein, a violinist, educator and arts administrator, represented Musicians For Harmony (and New York) by providing instruction in Strings and working with the Iraqi Unity Youth Orchestra. She also introduced the Suzuki violin teaching method to Iraqis for the first time in the country’s history.
She adds, “to be called “Teacher,” in three languages, no less )Kurdish, Arabic, and English), brings back memories of when I taught violin full-time, and that special satisfaction and sense of accomplishment that surpasses all other types of professional endeavors.”
The July Academy marked Klein’s second trip to Iraq as a “cultural ambassador.” In November 2003, she attracted international attention by traveling to Baghdad on behalf of Musicians For Harmony to present much needed funds and musical instruments to the Iraqi National Symphony Orchestra, playing with the orchestra during one of their rehearsals and fostering hope and goodwill among her Iraqi counterparts. Her close ties to the INSO have continued in the years since.
There is a link below to Musicians For Harmony’s webpage devoted to Klein’s experiences at the Erbil Academy.
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Klein’s reputable organization Musicians For Harmony continues to deliver on the promise of its mission to promote peace and cultural diplomacy through music. The non-profit, founded shortly after September 11, 2001, presents a “Concert For Peace” in New York City each Fall, featuring internationally renowned classical and world music artists. In an indication of its growing stature, Musicians For Harmony has just been awarded its first-ever grant from New York City’s Department of Cultural Affairs.
This year, Musicians For Harmony celebrates its Sixth Annual “Concert For Peace” with a September 11, 2007 performance at Symphony Space. At this special event, international stars will share the stage with acclaimed classical musicians for what promises to be a memorable evening. The concert will feature three world premieres, as unique instruments including the kora and pipa will be showcased alongside more familiar classical fare.
Featured artists include pianist Claude Frank with Arnold Steinhardt, violin, Michael Tree, viola and Peter Wiley, cello (Guarneri Quartet) performing Mozart’s Piano Quartet in G minor; the return of The Shanghai Quartet performing Ravel; virtuoso pipa player Wu Man, who will perform a world premiere solo piece “Soliloquio Serrano” by the Peruvian-Jewish-Chinese composer Gabriela Lena Frank; and Musique Sans Frontires, who will be joined by Malian kora player Yacouba Sissoko for two world premiere performances, “Siya” by Sissoko and “Couleurs du March” by MFH’s Artistic Director, Patrick Derivaz. Also on the program are Colin Jacobsen, violin, and his brother Eric Jacobsen, cello, who will accompany Wu Man on a piece titled “NING” by Chen Yi. WNYC’s ‘Soundcheck’ is expected to air a live broadcast on 9/11 at 2pm, featuring pre-concert interviews with Wu Man and Colin and Eric Jacobsen.
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Posted by john on August 15th, 2007 — in Allegra Top News
Allegra McCullough recently accepted the position of co-chair on The American Small Business Coalition Advisory Board where she will share duties with Mark Amtower, inaugural advisory board chairman. In this role she will participate in providing insight and guidance to The ASBC Executive Team in the development of educational and assistance programs to government contractors. Ms. McCullough is a former Associate Deputy Administrator at the U.S. Small Business Administration in the Office of Government Contracting, and has served on The ASBC Advisory Board since 2006.
Allegra F. McCullough accepts Co-Chair position on The American Small Business Coalition Advisory Board
During her term as Associate Deputy Administrator, Ms McCullough was responsible for the delivery of SBA’s procurement assistance programs to assist small businesses seeking to sell their products and services to the federal government. She directed the Agency’s business development programs which included the 8(a) Business Development and Small Disadvantaged Business Programs as a well as the Historically Underutilized Business Zones (HUBZone) Program and procurement assistance programs to ensure that small businesses received their fair share of federal procurement contracts.
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Prior to assuming the ADA/GCBD position, Ms. McCullough was appointed Regional Administrator for the U.S. Small Business Administration’s Mid-Atlantic Region (Region 3) and also served as the Director of the Department of Minority Business Enterprise for Virginia.
About The American Small Business Coalition
The American Small Business Coalition facilitates relationship development and information access for small companies doing business in the government sector. Through the unique and innovative Business-Select Membership program, companies receive industry-specific advisory and technical support as they pursue business opportunities wth government agencies and other government contractors. Agency officials can participate with The ASBC for outreach activities and to identify industry partners in support of mission requirements. The ASBC Community consists of small, medium, and large companies located around the United States and the globe, and U.S. Government agencies at the local, state and federal levels.
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Posted by john on August 10th, 2007 — in Allegra Top News
Children who suffer from hay fever, due to allergies to mold or pollen, are less likely to go on to develop asthma if they get immunotherapy to combat their sensitivity to allergy-triggers, researchers say.
Immunotherapy aims to build up tolerance to substances that set off allergic reactions by slowly exposing the affected person to gradually increasing doses of the allergen, either by injections or administration under the tongue. The process can take months or years to achieve full desensitization.
The current study, a follow-up of the Preventive Allergy Treatment (PAT) study, showed that specific immunotherapy for children with hay fever, or “seasonal allergic rhinoconjunctivitis,” helps prevent the development of asthma for up to 7 years after treatment ends.
The PAT study investigated whether the effects of 3 years of immunotherapy persist in children with seasonal allergic rhinoconjunctivitis caused by birch and/or grass pollen allergy as they grow up. The results at 10 years after the start of treatment are reported in the medical journal Allergy.
Dr. L. Jacobsen from ALK-Abello, Horsholm, Denmark and colleagues found that, among 117 children who were free of asthma at the start of the study, those given immunotherapy were 4.6 times more likely than those treated with an inactive “placebo” to remain free of asthma during the 10 years of follow-up.
Of 53 patients given placebo, 24 developed asthma, whereas among the 64 patients in the immunotherapy group, 16 became asthmatic.
Furthermore, the beneficial effect of immunotherapy in easing allergy symptoms, like runny noses and itchy eyes, also persisted 7 years after completion of 3 years of treatment.
“This 10-year follow-up study demonstrates that specific immunotherapy for 3 years with high-dose standardized allergen extracts shows persistent long-term effect on clinical symptoms after termination of treatment and long term, preventive effect on later development of asthma in children with seasonal rhinoconjunctivitis,” Jacobsen’s team concludes.
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Posted by john on August 6th, 2007 — in Allegra Top News
Albany Molecular Research Inc. (AMRI) has posted encouraging financial results in the second quarter of the year, boosted by both bigger royalty payments and steady growth in its contract business.
In addition, the company recorded a $6.5m operating income in the quarter, a substantial improvement from the year-ago quarter when the company posted an operating loss of $1.1m. Although this included one-time charges of $2.2m related to the company’s former research centre in Mount Prospect near Chicago, Illinois.
Total revenue for the second quarter of 2007 was $49.4m (€35.9m), an 8 per cent increase compared to $45.6m in the second quarter of 2006.
Revenue was boosted by a $1.5m milestone payment resulting from the company’s licensing deal with Bristol-Myers Squibb (BMS) in the second quarter of 2007 as a compound being developed under the agreement will soon enter the preclinic, triggering payment to AMRI.
Meanwhile, recurring royalties from antihistamine drug Allegra (fexofenadine) in the period improved and reached $7.8m, an increase of 9 per cent compared $7.2m in 2006.
AMRI earns royalties from worldwide sales of Allegra, as well as the authorised generic, for patents relating to the active ingredient in the drug. Sales of Allegra have been stable in the last year following a massive drop at the end of 2005 due to the launch of a generic version by Barr and Teva Pharmaceuticals in the US
Since then the company has been increasingly relying on its contract services business which performed relatively well in the second quarter, generating $39.9m, up 4 per cent compared to $38.4m in the same quarter last year. The business includes discovery services, small scale manufacturing and large scale manufacturing services.
The best performer of the contract business was the development and small scales manufacturing segment which generated a $10.6m in the quarter, a 25 per cent increase compared to $8.5m in the second quarter of last year. The company said the improvement results from “continued strong demand for this type of services”.
Sales in the discovery services segment also increased, by 6 per cent to $9.7m, an jump attributed by the company to “higher demand for these services in the US and Singapore”.
In contrast, revenue from large scale manufacturing in the second quarter of the year was $19.6 million, a 5 per cent decline from $20.8m in the second quarter of 2006.
“The decrease resulted from the timing of certain large scale clinical development manufacturing projects,” AMRI said, adding that it expected to recover revenue from most of these projects in the second half of the year.
The company, which has suffered of late from sub-optimal profitability at its large scale manufacturing facility in Renhsselaer, New York, recently signed a definitive agreement to acquire two pharmaceutical production sites in India for $11m.
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Posted by john on July 29th, 2007 — in Allegra Top News
London is said to have the highest concentration of Starbucks in the world, with more branches in the capital than in Manhattan. Yet Britain’s colonisation by cappuccino culture has not yet run its course, with analysts predicting that the leading operators might double in size within the next decade – an expansion that could mean the days of the local tea shop and greasy spoon are numbered.
Just over 10 years after Starbucks opened its first British branch, the nation now boasts more than 3,000 branded coffee shops. The research group Allegra Strategies predicts the store count will keep growing at 9 per cent a year, rising above 6,000 outlets within a decade, creating an industry that generates an annual turnover of more than £2.5bn. Some in the industry are even more ambitious, with management at Whitbread, the owner of Costa Coffee, saying there is scope for the chain to grow to more than 1,000 outlets by 2010, from 560 currently.
Those projections are at odds with the views of many commentators, who have long been claiming that the capital’s premium coffee market is nearing saturation point. More than half of Starbucks’ 540 UK coffee shops are in the Greater London area, with new ones opening at a rate of one a fortnight.
While industry insiders dismiss that concern, they concede that companies will have to start looking further afield for growth. “Much of the future expansion will come from rural areas, where independent operators still have the upper hand. The next battleground will be in population centres of around 30,000,” says one.
That prospect has alarmed campaigners who fear Britain is becoming a nation of clone towns with identikit high streets.
Customer research suggests those independents will have to work a lot harder to survive. They continue to have a bigger slice of the market than any of the chains, with a combined 38 per cent share against Starbucks and Costa Coffee on 24 per cent each. But Allegra’s survey reveals that just 12 per cent of consumers picked an independent as their vendor of choice.
Jeffrey Young, Allegra’s managing director, says that small operators should be in a strong position to fight their corner, as convenience of location is the biggest single factor on where consumers choose to drink their lattes. But he argues that they have been naive, believing that personal service alone will be enough to keep the market leaders at bay.
The big brands, meanwhile, have created a totally new market in the last decade simply by cutting out the clutter.
“When trading head-to-head, there’s an enormous amount of brand pull from the chains,” says Mr Young. “The large operators tend to be better run and better managed, so an independent needs to be offering something exceptional to stand out.”
That view is echoed within the industry, where there have been some notable success stories at the artisan end of the market. Flat White, an award-winning café in London’s Soho that opened two years ago, has carved out a niche by specialising in a no-expense-spared version of the Antipodean-style frothy coffee from which it takes its name. The company is now looking to expand.
“What we offer over the chains is a much higher attention to detail and more of a community feel,” says Cameron McClure, the New Zealander who was one of Flat White’s founder baristas.
“The big guys are really just making coffee drinking more widespread, which ends up creating demand for us.
“Those people who can tell the difference end up searching out something better. Our business works by taking an artisan approach that’s much more labour intensive than the competition are able to offer.”
Flat White buys its beans from The Monmouth Coffee Com-pany, another small, London-based operator that has thrived in the face of competition by adopting an approach more akin to fine wine than coffee.
Such successes, the multinationals claim, are proof that the market is big enough for everyone to thrive. A Starbucks spokesman, highlighting research showing that 20 per cent of all independent coffee shops in Britain started less than a year ago, claims this shows how the domination by the main chains is not stifling competition.
It is no secret why new entrants are trying their luck. The gross profit margin on the average cup of chain coffee is estimated to be around 85 per cent, with sensitivity to price rises extremely low. Accounting for the gradual move from medium to grande, the price for an average cup has risen by some 40 per cent since 1999, nearly twice the rate of inflation.
Yet the leading companies are still struggling to keep their investors happy. Shares in Starbucks, which posts quarterly results on Wednesday, have fallen more than 20 per cent so far this year on worries about weaker discretionary spending and rising dairy and labour costs.
There has also been renewed talk of competition within Starbucks’ home market, as fast-food restaurants and doughnut shops invest in proper brewing equipment and introduce higher-quality blends. “While we view the direct competitive domestic threat as being limited, it is not non-existent,” Citigroup analyst Glen Petraglia said in a recent research note.
Arguably, the main source of competition in the UK is coming from pub operators. JD Wetherspoon launched its gourmet coffee product last year with a publicity campaign deriding the “rip-off” prices of its rivals. It claims to have picked up 6 per cent of the UK chain market already, with volumes matching the third-place operator, Caffè Nero. However, analysts doubt whether these sales have been at the expense of the multinationals.
“They are making no real inroads in the branded market, because they are selling a different proposition,” says Mr Young. “Overwhelmingly, customers consider where they drink their coffee as a lifestyle choice. McDonald’s, despite all its investment in improving its coffee, has not been able to replicate the same lounging experience, while pubs are still viewed first and foremost as places for drinking.”
The ever-expanding market has also turned the spotlight on the industry’s environmental credentials, with some claiming that the multinationals operate a buying cartel. Starbucks alone accounts for around 14 per cent of total global Fairtrade coffee imports, but in common with its biggest rivals, the beans used for basic espresso are purchased under its own code of conduct.
While customers rate environmental concerns down the list of priorities, that situation is unlikely to change, according to Mr Young. “Fairtrade has become a must-have on your menu, but it has little influence on consumer decisions,” he says. “People do not make a decision based on ethical credentials. While they like seeing the Fairtrade logo, they’re simply not prepared to pay any more for it.”
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Posted by john on July 25th, 2007 — in Allegra Top News
JESSICA Rowe has revealed she felt “ashamed” to admit she was battling post-natal depression, despite her strong history of mental health advocacy.
The new Seven Network recruit said yesterday that her traumatic tenure at the Today show coupled with the long and painful fertility treatment she endured to conceive contributed to her decline after the birth of her daughter, Allegra, in January.
However, her stunning admission has been applauded by depression support groups and sufferers for shedding more light on the dark disease.
The 37-year-old will return to Australian TV screens as a contestant on Channel 7’s Dancing With the Stars.
It was after nominating national mental health initiative beyondblue as the charity she would dance to raise funds for that Rowe conceded she “had to be true to myself and admit I’d suffered (from post-natal depression)'’.
“At first I had planned to put it behind me. I’d recovered and wanted to move forward,'’ she said.
Rowe told New Idea she had tried to ignore the symptoms, which she knew were more than just sleep deprivation and the normal hormone changes women encounter after giving birth.
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“I was getting very anxious. I felt out of control. I worried about everything, like whether she’d get a cold - but beyond normal levels. I also had trouble breast-feeding,'’ she said.
Rowe told The Daily Telegraph: “It also shocked me that I felt so ashamed of admitting it. Of not coping.'’
But her close work with depression support groups and her family experience with mother Penny, who has battled bipolar disorder, forced her to admit she needed to seek help quickly.
“If I hadn’t done that, my recovery process would have been so much longer.'’
After four attempts at IVF, Rowe said her desperate longing for her child made her depression harder to admit.
“I felt ashamed. How could I feel like this when I finally had this beautiful treasure?'’
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Posted by john on July 22nd, 2007 — in Allegra Top News
People suffering from chronic sinusitis—inflamed mucous membranes in the sinus cavities surrounding the nose—often have to see an otolaryngologist (ear, nose and throat, or ENT, specialist) an allergist and a pulmonologist to treat their symptoms. This can result in multiple doctor appointments and increased time off work.
“The respiratory system is one tract, so it’s common for patients to suffer from nasal and sinus problems as well as lower respiratory conditions such as asthma,” says Allen Seiden, MD, an otolaryngologist at UC. “They may need to see an allergist, an ENT specialist and a pulmonologist because each one treats different aspects of the respiratory system.”
To help expedite diagnosis and treatment, the University of Cincinnati (UC) is opening the first comprehensive respiratory center in the region.
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Seiden and UC colleague Lee Zimmer, MD, are partnering with allergists Lawrence Newman, MD, and Steven Sutton, MD, to treat allergy and sinus sufferers in one location—the University Sinus and Allergy center at University Pointe in West Chester.
Prior to their visit, patients are screened and appointments scheduled with multiple specialists in one location on the same day. They may be evaluated by an otolaryngologist and an allergist during their visit and undergo specialized diagnostic tests, such as nasal endoscopy, allergy testing, bronchoscopy and pulmonary function testing.
The specialists will collaboratively discuss each patient’s case and develop a comprehensive, multidisciplinary treatment plan.
“By working together, we have a much broader perspective on treatment, and we hope this leads to better control for a patient’s condition,” says Seiden.
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Posted by john on July 17th, 2007 — in Allegra Top News
More and more foods bear a mishmash of warnings that they might accidentally contain ingredients that could sicken people with food allergies.
Yet there are signs that the new labels are instead creating confusion for families that should heed them.
About 12 million Americans have some food allergy; such allergies trigger 30,000 emergency-room visits a year.
A law that took effect last year requires foods that by design contain highly allergenic ingredients such as peanuts or shellfish to disclose that in plain language.
The accidental-allergy labels are different. They are aimed at foods that shouldn’t contain an allergen but might get contaminated: made in the same factory or on the same machines as allergen-containing goods.
University of Nebraska food scientist Steve Taylor tested 179 products that bore a variety of accidental-peanut warnings and found that 7 percent did contain peanuts.
Peanuts were in 2 of 51 foods that bore a “may contain” warning and 7 of 68 labeled “made in the same facility.”
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The Food Allergy & Anaphylaxis Network, an influential consumer group, surveyed more than 600 parents of food-allergic children. In 2006, 75 percent said they would never buy a food with an accidental-allergy warning — down from 85 percent when the network posed the same question in 2003.
Worried that the labels may be losing credibility, the Food and Drug Administration is considering whether to intervene.
Penny Ackerman of Bethlehem, Pa., is strict about label reading to protect her 3-year-old son, Gregory, who is severely allergic to peanuts.
On a recent grocery trip, Ackerman didn’t notice until she got home that the chocolate chips she had always bought with confidence now carried a new warning that they were made in a factory that uses peanuts. She wonders whether the chips are made in a new factory, or whether the company hadn’t gotten around to labeling until now.
“If you don’t see it on the label, is it safe or is it not safe?” she said. “Because you don’t know.”
Consumers see the label “on so many products, they say, ‘Oh heck, I’m going to ignore it,’” said Taylor, a situation he says is akin to playing Russian roulette.
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Posted by john on July 15th, 2007 — in Allegra Top News
I may be a savvy woman but when I’m sick, I’m a wimp. The worst thing about being single is getting sick. It’s hard to recuperate when you have to fetch your own bowl of soup and prepare a warm towel for your forehead.
This past week, I had ran out of my allergy medication which means I was in for a bout of an allergy attack. I called my specialist to get a 10-day prescription of Allegra-D until my refill came in through mail order.
The receptionist that answered the phone didn’t tell me the first time that my specialist wouldn’t be in until later in the afternoon. It wasn’t until I called a second time that I found out that I would have a long wait.
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I told her in a distressed voice that I’m single and I don’t have anyone to pick up my medicine later and that I needed it right now. I was about to lose my mind because I felt like she didn’t understand. I was polite but I was frustrated.
My plan B was to call my regular physician and she was able to come through with some samples.
I can do a lot of things that independence shapes you to do, but when I’m ill, I don’t mind saying I need help. Those of you who have a spouse or significant other should know how fortunate you are that you have someone to take care of you in your time of need.
For the rest of us single ladies, we’ll have to pray for our Boaz to show up soon
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